First, pull the carbs and see what jets you have to begin with.
1 jet size for custom 4 into 2 exhaust
2 jet sizes for 4 into 1 exhaust
1 jet size for K&N filter (single inside airbox)
1 jet size for drilling out the bottom of the airbox
3 jet sizes for individual filters
2 jet sizes for no muffler (open header)
1 pilot jet size for every 3 main jet size increase
Add up all the jet size increases and subtract one. (They go in steps of 2.5 for each jet size)
Or, you could just get a wideband o2 sensor and tune it accordingly.