Thanks Ribo.
As I said, I kept both overhead doors open (and the door to the house firmly closed) and it was a fairly breezy day. I ended up with a few specks of dust because I wasn't in a sealed, proper paint booth, but again, this is basically a sub-$100 paint job so I'm pretty happy with the results and most folks are really surprised when I tell them I painted the tank and covers myself with rattle cans in the garage. I did a fair bit of research into protective measures since I didn't really want to die for a paint job or give myself asthma to save a few bucks. As far as I know, once everything has settled and dried a bit (and you've kept the overspray off of yourself and not touched with bare skin anything it has landed on) it's all quite innocuous. After my final coat I left the garage through the over head doors and didn't use the house door for the next hour or so. Upon returning to the garage there was no noticeable odors or anything that would indicate too much lingering threat (I realize this is very unscientific, but I'm just recounting my own experience with the stuff.) I suppose I'll get back to you in 40 years or so if I've not caused irreparable harm, but I'm confident that the protections I employed, and the relative scale of exposure - 1 tank, 2 side covers - is really quite minimal but I also understand your concern. It is odd that you've not yet figured out a way to lock up your loved ones, maybe practice your TIG welding by assembling a nice cage or pen... Something to consider.
The drying time on the clear was fairly quick. I waited over a week after shooting the acrylic enamel as per the instructions on the can to allow for it to fully cure, then applied the decals, wiped them clean of any excess adhesive, then shot the clear on a breezy day with low humidity and an outside temperature of about 20c (or 70-ish Fahrenheit? I dunno, crazy Yankee temperatures...) The next afternoon I wet sanded some small runs (I'm not overly experienced and my goggles were fogging up - that's my excuse, anyway!) and buffed everything and went about my merry way... straight into brake caliper rebuilding...
Anyway, sorry for the diatribe, just trying to give as much information on my experience trying the 2k as possible. All in all it was fairly straightforward and I'm happy with the result. It seemed to work out just fine and I'm not left with a paint job that cost more than the bike it went on.