I've pretty much got the 592 hot rod motor jetted with the stock carbs. I'm getting miles on the bike now and will re-torque the head and degree the cam (hopefully). Then next step is put in the carb set that Rick Denoon has bored to 28mm, get the jetting close and then go to the Dyno with stock carbs and the Denoon overbored carbs. Here are my findings currently with the stock carbs.
Engine - Fully modified CB550 for street use:
Dynoman 592 piston kit 10.5 compression ratio, Webcam 58B, ported head, Kipplewhite racing valve springs, Dyna 2 Ignition and coils, Mac Exhaust, Barnett Clutch kit, Carbs are 75-77 CB550F which are labelled 069A, plugs are NGK DR-7ES, Uniflow Pod air filters.
Carb 069A final settings
Main Jet #120
Needle - Stock in stock clip position (2nd from top)
Pilot Jet - #38 (stock)
Air Screw - 2 turns out
The bike runs quite well, a little burble and hesitation at 2000rpm but pretty clean thereafter, steady 1200 rpm idle. Very strong from about 6500 rpm to 11000 rpm. When I say very strong I mean an absolute rocket ship!! I might try raising float level to clean up the bottom end a bit more. Currently I'm at 22mm float level which is stock and others have gone as far as 27mm to get good results at bottom and mid range response.
I agree that you must get main jet sorted first, forget everything else and get some wide open throttle plug chops to set the size of main. Everything else will fall into line IF you do the main jet properly and do it FIRST. Otherwise, everything is a guess and super frustrating.